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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2006-11-6
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pubmed:abstractText |
Previous gene transfection studies have shown that the accumulation of human ribonucleotide reductase small subunit M2 (hRRM2) enhances cellular transformation, tumorigenesis, and malignancy potential. The latest identified small subunit p53R2 has 80% homology to hRRM2. Here, we investigate the role of p53R2 in cancer invasion and metastasis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/RRM2B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ribonucleoside Diphosphate Reductase,
http://linkedlifedata.com/resource/pubmed/chemical/Ribonucleotide Reductases,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53,
http://linkedlifedata.com/resource/pubmed/chemical/ribonucleotide reductase M2
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:ChuPeiguoP,
pubmed-author:JOBJ CJC,
pubmed-author:LinWesleyW,
pubmed-author:LiuXiyongX,
pubmed-author:PalR NRN,
pubmed-author:QiChristinaC,
pubmed-author:ShihJenniferJ,
pubmed-author:TyeKarenK,
pubmed-author:UnFrankF,
pubmed-author:XueLijunL,
pubmed-author:ZhouBingsenB
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6337-44
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17085643-Adenocarcinoma,
pubmed-meshheading:17085643-Blotting, Western,
pubmed-meshheading:17085643-Cell Cycle Proteins,
pubmed-meshheading:17085643-Cell Line, Tumor,
pubmed-meshheading:17085643-Cell Movement,
pubmed-meshheading:17085643-Colonic Neoplasms,
pubmed-meshheading:17085643-Humans,
pubmed-meshheading:17085643-Immunohistochemistry,
pubmed-meshheading:17085643-Neoplasm Invasiveness,
pubmed-meshheading:17085643-RNA, Small Interfering,
pubmed-meshheading:17085643-Ribonucleoside Diphosphate Reductase,
pubmed-meshheading:17085643-Ribonucleotide Reductases,
pubmed-meshheading:17085643-Transfection,
pubmed-meshheading:17085643-Tumor Markers, Biological,
pubmed-meshheading:17085643-Tumor Suppressor Protein p53
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pubmed:year |
2006
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pubmed:articleTitle |
Metastasis-suppressing potential of ribonucleotide reductase small subunit p53R2 in human cancer cells.
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pubmed:affiliation |
Department of Clinical and Molecular Pharmacology, City of Hope National Medical Center, Duarte, California 91010-3000, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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