Source:http://linkedlifedata.com/resource/pubmed/id/17075013
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2006-11-7
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pubmed:abstractText |
We previously hypothesized that high activity of creatine kinase, the central regulatory enzyme of energy metabolism, facilitates the development of high blood pressure. Creatine kinase rapidly provides adenosine triphosphate to highly energy-demanding processes, including cardiovascular contraction, and antagonizes nitric oxide-mediated functions. Relatively high activity of the enzyme, particularly in resistance arteries, is thought to enhance pressor responses and increase blood pressure. Tissue creatine kinase activity is reported to be high in black people, a population subgroup with greater hypertension risk; the proposed effects of high creatine kinase activity, however, are not "race dependent." We therefore assessed whether creatine kinase is associated with blood pressure in a multiethnic population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1524-4539
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
7
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2034-9
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pubmed:meshHeading |
pubmed-meshheading:17075013-Adult,
pubmed-meshheading:17075013-African Continental Ancestry Group,
pubmed-meshheading:17075013-Asian Continental Ancestry Group,
pubmed-meshheading:17075013-Blood Pressure,
pubmed-meshheading:17075013-Creatine Kinase,
pubmed-meshheading:17075013-European Continental Ancestry Group,
pubmed-meshheading:17075013-Female,
pubmed-meshheading:17075013-Humans,
pubmed-meshheading:17075013-Hypertension,
pubmed-meshheading:17075013-Male,
pubmed-meshheading:17075013-Middle Aged,
pubmed-meshheading:17075013-Netherlands,
pubmed-meshheading:17075013-Suriname
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pubmed:year |
2006
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pubmed:articleTitle |
Creatine kinase activity is associated with blood pressure.
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pubmed:affiliation |
Department of Internal Medicine, F4-222, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. mail@lizzybrewster.net
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pubmed:publicationType |
Journal Article,
Comparative Study
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