Both N-methyl-D-aspartate receptor antagonists and nonsteroidal anti-inflammatory drugs have been demonstrated to produce better postoperative pain relief. The concept of multimodal analgesia has also been used for clinical pain management. The aim of the present study was to examine the analgesic effect of preoperative cotreatment with dextromethorphan (DM) and ketorolac on postoperative pain management after laparoscopic-assisted vaginal hysterectomy (LAVH).
Department of Anesthesiology, Tri-Service General Hospital and, National Defense Medical Center, no. 325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan, Republic of China.