Source:http://linkedlifedata.com/resource/pubmed/id/17057209
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2006-10-23
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pubmed:abstractText |
On the basis of several studies that have been completed to date, some growth factors appear promising for the treatment of inflammatory bowel disease: keratinocyte-like growth factor-2 (KGF-2), epidermal growth factor (EGF) enemas used in combination with oral mesalamine, somatropin (human growth hormone), and sargramostim (recombinant human GM-CSF). The results of these studies are highlighted and suggest that new insights into the regulation of intestinal immunity may provide effective synergistic or single-agent treatment alternatives to immunosuppression for inflammatory bowel disease. These data focus on the reparative components of mucosal homeostasis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0077-8923
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1072
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
300-6
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pubmed:meshHeading |
pubmed-meshheading:17057209-Animals,
pubmed-meshheading:17057209-Colitis, Ulcerative,
pubmed-meshheading:17057209-Fibroblast Growth Factor 10,
pubmed-meshheading:17057209-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:17057209-Growth Substances,
pubmed-meshheading:17057209-Inflammatory Bowel Diseases,
pubmed-meshheading:17057209-Models, Animal,
pubmed-meshheading:17057209-Rats,
pubmed-meshheading:17057209-Rats, Inbred Lew
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pubmed:year |
2006
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pubmed:articleTitle |
Growth factors as treatment options for intestinal inflammation.
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pubmed:affiliation |
Division of Gastroenterology, Siteman Cancer Center, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA. dieck@im.wustl.edu
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pubmed:publicationType |
Journal Article
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