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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-10-26
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pubmed:abstractText |
Impairment in cell-mediated immunity has long been recognized in classical Hodgkin's lymphoma (cHL). The immunosuppressive environment at the tumor site and/or a primary T-cell defect may contribute to an ineffective immune clearance of Hodgkin/Reed-Sternberg (H/R-S) cells. Here, we analyzed whether circulating T lymphocytes of cHL patients show specific alterations in gene expression with possible impact on anti-tumor immunity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1010-4283
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2006 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-33
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pubmed:meshHeading |
pubmed-meshheading:17033203-Adult,
pubmed-meshheading:17033203-Antigens, CD3,
pubmed-meshheading:17033203-CD4-Positive T-Lymphocytes,
pubmed-meshheading:17033203-CD8-Positive T-Lymphocytes,
pubmed-meshheading:17033203-Female,
pubmed-meshheading:17033203-Gene Expression Profiling,
pubmed-meshheading:17033203-Hodgkin Disease,
pubmed-meshheading:17033203-Humans,
pubmed-meshheading:17033203-Immunity, Cellular,
pubmed-meshheading:17033203-Lymphocyte Count,
pubmed-meshheading:17033203-Male,
pubmed-meshheading:17033203-Middle Aged,
pubmed-meshheading:17033203-Neoplasm Staging,
pubmed-meshheading:17033203-RNA, Neoplasm,
pubmed-meshheading:17033203-T-Lymphocytes
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pubmed:year |
2006
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pubmed:articleTitle |
Classical Hodgkin's lymphoma: molecular evidence for specific alterations in circulating T lymphocytes.
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pubmed:affiliation |
Department of Hematology, Hemostaseology and Oncology, Hannover Medical School, Hannover, Germany. franzke.anke@mh-hannover.de
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pubmed:publicationType |
Journal Article
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