Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1991-2-26
|
pubmed:abstractText |
Separation of basophilic granulocytes from peripheral blood was carried out by counterflow centrifugation elutriation using a JE-6B roter. The release of histamine and heparin-like substance from basophilic leucocytes was estimated in healthy and asthmatic subjects. 1. The number of basophils was maximal (0.74 x 10(5] at a flow rate of 4.5 ml/min, and the purity reached a peak (11.8 +/- 2.0%) at a flow rate of 9 ml/min. 2. The content of histamine paralleled the number of basophils in each fraction. 3. The release mechanism of histamine induced by anti-IgE was similar to that of the heparin-like substance. 4. The release of histamine and the heparin-like substance was significantly higher in atopic asthmatics than in non-atopic cases.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0021-5120
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
356-61
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1703247-Adolescent,
pubmed-meshheading:1703247-Adult,
pubmed-meshheading:1703247-Aged,
pubmed-meshheading:1703247-Antibodies, Anti-Idiotypic,
pubmed-meshheading:1703247-Asthma,
pubmed-meshheading:1703247-Basophils,
pubmed-meshheading:1703247-Child,
pubmed-meshheading:1703247-Dose-Response Relationship, Drug,
pubmed-meshheading:1703247-Flow Cytometry,
pubmed-meshheading:1703247-Heparin,
pubmed-meshheading:1703247-Histamine Release,
pubmed-meshheading:1703247-Humans,
pubmed-meshheading:1703247-Immunoglobulin E,
pubmed-meshheading:1703247-Leukocyte Count,
pubmed-meshheading:1703247-Middle Aged
|
pubmed:articleTitle |
Release of heparin-like substance and histamine from basophilic leucocytes separated by counterflow centrifugation elutriation.
|
pubmed:affiliation |
Division of Medicine, Okayama University Medical School, Tottori, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|