Source:http://linkedlifedata.com/resource/pubmed/id/17030762
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
2006-10-10
|
pubmed:abstractText |
Mitochondrial dysfunction plays a major role in the pathogenesis of Parkinson disease (PD). Creatine (Cr) is an ergogenic compound that exerts neuroprotective effects in animal models of PD. We conducted a 2-year placebo-controlled randomized clinical trial on the effect of Cr in 60 patients with PD. Cr improved patient mood and led to a smaller dose increase of dopaminergic therapy but had no effect on overall Unified Parkinson's Disease Rating Scale scores or dopamine transporter SPECT.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1526-632X
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
10
|
pubmed:volume |
67
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1262-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:17030762-Administration, Oral,
pubmed-meshheading:17030762-Brain,
pubmed-meshheading:17030762-Creatine,
pubmed-meshheading:17030762-Dietary Supplements,
pubmed-meshheading:17030762-Double-Blind Method,
pubmed-meshheading:17030762-Female,
pubmed-meshheading:17030762-Humans,
pubmed-meshheading:17030762-Male,
pubmed-meshheading:17030762-Middle Aged,
pubmed-meshheading:17030762-Parkinson Disease,
pubmed-meshheading:17030762-Pilot Projects,
pubmed-meshheading:17030762-Placebo Effect,
pubmed-meshheading:17030762-Treatment Outcome
|
pubmed:year |
2006
|
pubmed:articleTitle |
Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial.
|
pubmed:affiliation |
Department of Neurology, Klinikum Grosshadern, Klinikum Grosshadern, University of Munich, Germany.
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|