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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-2-19
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pubmed:abstractText |
From June 1981 to June 1989 we diagnosed 174 cases of hepatocellular carcinoma (HCC) at our institution (Piacenza, Northern Italy). Average age was 65.6 years; male to female ratio 3.4. 149 patients were cirrhotic (85.6%); alcohol abuse was present in 88/169 (52.1%); in 53/145 patients all hepatitis B virus markers were negative. Alpha-fetoprotein showed a low diagnostic sensitivity (values above 500 ng only in 49/169 or 29.0%). We used ultrasound (US) examination with a very high identification rate in all cases; pathological diagnosis was achieved by US guided fine-needle aspiration biopsy in 135 patients; in 13, by laparoscopy-histology. Metastases were found in 24/169 cases (14.2%); a second malignancy was diagnosed in 13/169 (7.7%): the most common association was HCC-non-Hodgkin lymphoma. Only 14 patients could be referred to surgery, which significantly improved prognosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
26-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1702884-Adult,
pubmed-meshheading:1702884-Aged,
pubmed-meshheading:1702884-Aged, 80 and over,
pubmed-meshheading:1702884-Carcinoma, Hepatocellular,
pubmed-meshheading:1702884-Cytodiagnosis,
pubmed-meshheading:1702884-Female,
pubmed-meshheading:1702884-Follow-Up Studies,
pubmed-meshheading:1702884-Hepatitis B,
pubmed-meshheading:1702884-Humans,
pubmed-meshheading:1702884-Liver Neoplasms,
pubmed-meshheading:1702884-Male,
pubmed-meshheading:1702884-Middle Aged,
pubmed-meshheading:1702884-alpha-Fetoproteins
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pubmed:year |
1991
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pubmed:articleTitle |
Diagnostic aspects and follow-up of 174 cases of hepatocellular carcinoma. Second report.
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pubmed:affiliation |
First Division of Internal Medicine, Hospital of Piacenza, Italy.
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pubmed:publicationType |
Journal Article
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