Source:http://linkedlifedata.com/resource/pubmed/id/17011627
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2006-12-12
|
pubmed:abstractText |
Using vanadate, poly(1H-pyrazol-1-yl)borate and pyrazole as starting materials, two new neutral peroxovanadium(V) complexes with poly(1H-pyrazol-1-yl)borate, VO(O(2))(pzH)(HB(pz)(3))(1) and VO(O(2))(pzH)(B(pz)(4))(2), were synthesized successfully. Both complexes were characterized by elemental analysis, IR, UV-vis and NMR spectra. And the structure of complex 1 was determined by X-ray diffraction, which is somewhat relevant for haloperoxidase enzymes. Cytotoxic effects also are discussed on 3T3 cell proliferation. In the concentration range (0.1-100mumol), both complexes have an inhibiting cellular proliferation effect. When the cells cultivated with the complexes at high dose, the toxicity effect of both complexes is more and more predominant.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0162-0134
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
101
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
36-43
|
pubmed:meshHeading |
pubmed-meshheading:17011627-Magnetic Resonance Spectroscopy,
pubmed-meshheading:17011627-Models, Molecular,
pubmed-meshheading:17011627-Molecular Structure,
pubmed-meshheading:17011627-Peroxidases,
pubmed-meshheading:17011627-Pyrazoles,
pubmed-meshheading:17011627-Spectrophotometry, Infrared,
pubmed-meshheading:17011627-Spectrophotometry, Ultraviolet,
pubmed-meshheading:17011627-Vanadium Compounds,
pubmed-meshheading:17011627-X-Ray Diffraction
|
pubmed:year |
2007
|
pubmed:articleTitle |
Two new scorpionates vanadium haloperoxidases model complexes: synthesis and structure of VO(O2)(pzH)(HB(pz)3) and VO(O2)(pzH)(B(pz)4) (pzH = pyrazole(C3H4N2)).
|
pubmed:affiliation |
Bioinorganic Laboratory, Liaoning Normal University, Dalian 116029, PR China. yhxing2000@yahoo.com
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|