Sphingolipids are known to play an important role in both water retention and epidermal permeability barrier function in mammalian stratum corneum. However, little is known about the effects on epidermal function of orally administered sphingolipids.
Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Pharmaceutical Sciences and Faculty of Advanced Life Sciences, Hokkaido University, Nishi 6, Kita 12, Kita-ku, Sapporo 060-0812, Japan.