Linked Life Data

16997141

Source:http://linkedlifedata.com/resource/pubmed/id/16997141

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19-20
pubmed:dateCreated
2006-9-25
pubmed:abstractText
In vitro display technologies, especially ribosome display, are valuable tools for many applications. In this paper, ribosome display technology and its applications for directed evolution of functional proteins will be reviewed. Ribosome display has great potential for directed evolution of protein stability and affinity, the generation of high-quality libraries by in vitro preselection, the selection of enzymatic activities, and the display of cDNA and random-peptide libraries. Ribosome display is carried out fully in vitro, which overcomes some of the limitations of cell-based display systems. We anticipate that ribosome display will have a great impact on applications in biotechnology, medicine and proteomics.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1359-6446
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
911-6
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Ribosome-display technology: applications for directed evolution of functional proteins.
pubmed:affiliation
Antibody Engineering Center, Key Laboratory of Animal Molecular Nutrition, Ministry of Education, Feed Science Institute, Zhejiang University, Hangzhou, 310029, P.R. China.
pubmed:publicationType
Journal Article, Review