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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2006-9-25
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pubmed:abstractText |
We examined the role of caveolae and caveolin-1 in the mechanism of 1alpha,25(OH)(2)D(3) action in growth plate chondrocytes. We found that caveolae are required for rapid 1alpha,25(OH)(2)D(3)-dependent PKC signaling, and caveolin-1 must be present based on studies using chondrocytes from Cav-1(-/-) mice.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0884-0431
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1637-47
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16995819-Animals,
pubmed-meshheading:16995819-Caveolae,
pubmed-meshheading:16995819-Caveolin 1,
pubmed-meshheading:16995819-Cells, Cultured,
pubmed-meshheading:16995819-Chondrocytes,
pubmed-meshheading:16995819-Growth Plate,
pubmed-meshheading:16995819-Male,
pubmed-meshheading:16995819-Mice,
pubmed-meshheading:16995819-Mice, Inbred BALB C,
pubmed-meshheading:16995819-Mice, Knockout,
pubmed-meshheading:16995819-Microscopy, Electron, Transmission,
pubmed-meshheading:16995819-Protein Kinase C,
pubmed-meshheading:16995819-Rats,
pubmed-meshheading:16995819-Rats, Sprague-Dawley,
pubmed-meshheading:16995819-Signal Transduction,
pubmed-meshheading:16995819-Vitamin D
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pubmed:year |
2006
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pubmed:articleTitle |
Regulation of growth plate chondrocytes by 1,25-dihydroxyvitamin D3 requires caveolae and caveolin-1.
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pubmed:affiliation |
Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, USA. barbara.boyan@bme.gatech.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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