Linked Life Data

16977346

Source:http://linkedlifedata.com/resource/pubmed/id/16977346

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-4-30
pubmed:abstractText
Recent reports have proven the importance of genetic factors and inflammation in the pathogenesis of rheumatoid arthritis (RA). In the current study, the frequency of NOD2/CARD15 gene variants (R702W, G908R, and L1007fsinsC) was examined in a group of 243 RA patients and 220 healthy controls. There were no statistically significant differences in distribution of NOD2 variant alleles between RA patients and controls. Moreover, there was no significant association between NOD2 variant alleles and joint erosions, extraarticular manifestations, rheumatoid factor, number of swollen and tender joints, and erythrocyte sedimentation rate. The results of the present study suggest that NOD2 allele variants have no significant influence on RA susceptibility, activity, and severity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0770-3198
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
868-71
pubmed:dateRevised
2008-5-13
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
NOD2 allele variants in patients with rheumatoid arthritis.
pubmed:affiliation
Department of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, ul. Powst.Wlkp. 72, Szczecin, 70-111, Poland. pawand@poczta.onet.pl
pubmed:publicationType
Journal Article