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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6287
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pubmed:dateCreated |
1990-10-4
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pubmed:abstractText |
Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules. Roughly one in 10(10) random sequence RNA molecules folds in such a way as to create a specific binding site for small ligands.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
346
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
818-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1697402-Base Sequence,
pubmed-meshheading:1697402-Binding Sites,
pubmed-meshheading:1697402-Chromatography, Affinity,
pubmed-meshheading:1697402-Cloning, Molecular,
pubmed-meshheading:1697402-Coloring Agents,
pubmed-meshheading:1697402-DNA,
pubmed-meshheading:1697402-Ligands,
pubmed-meshheading:1697402-Molecular Sequence Data,
pubmed-meshheading:1697402-Molecular Structure,
pubmed-meshheading:1697402-Nucleic Acid Conformation,
pubmed-meshheading:1697402-Polymerase Chain Reaction,
pubmed-meshheading:1697402-RNA,
pubmed-meshheading:1697402-Templates, Genetic,
pubmed-meshheading:1697402-Transcription, Genetic,
pubmed-meshheading:1697402-Triazines
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pubmed:year |
1990
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pubmed:articleTitle |
In vitro selection of RNA molecules that bind specific ligands.
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pubmed:affiliation |
Department of Molecular Biology, Massachusetts General Hospital, Boston 02114.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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