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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-12-22
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pubmed:abstractText |
Intrahepatic renin-angiotensin-aldosterone system (RAAS) plays a key role in the fibrogenesis of liver. However, the signal transduction mechanism underlying effects of Angiotensin II (Ang II) and Aldosterone (Aldo) on Nuclear Factor-kappaB (NF-kappaB) and active protein-1 (AP-1) pathway in hepatic fibrogenesis remains to be fully elucidated. The present study aims to investigate the signal transduction mechanism underlying effects of Ang II and Aldo on NF-kappaB and AP-1 pathway during hepatic fibrogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0167-0115
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-25
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pubmed:meshHeading |
pubmed-meshheading:16971004-Active Transport, Cell Nucleus,
pubmed-meshheading:16971004-Aldosterone,
pubmed-meshheading:16971004-Angiotensin II,
pubmed-meshheading:16971004-Animals,
pubmed-meshheading:16971004-Cells, Cultured,
pubmed-meshheading:16971004-Liver,
pubmed-meshheading:16971004-Liver Cirrhosis, Experimental,
pubmed-meshheading:16971004-Male,
pubmed-meshheading:16971004-NF-kappa B,
pubmed-meshheading:16971004-Rats,
pubmed-meshheading:16971004-Rats, Wistar,
pubmed-meshheading:16971004-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16971004-Signal Transduction,
pubmed-meshheading:16971004-Time Factors,
pubmed-meshheading:16971004-Transcription Factor AP-1,
pubmed-meshheading:16971004-Tumor Necrosis Factor-alpha,
pubmed-meshheading:16971004-Vasoconstrictor Agents
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pubmed:year |
2007
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pubmed:articleTitle |
Angiotensin II and Aldosterone stimulating NF-kappaB and AP-1 activation in hepatic fibrosis of rat.
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pubmed:affiliation |
Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. mylx99@163.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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