Source:http://linkedlifedata.com/resource/pubmed/id/16969797
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2006-9-18
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pubmed:abstractText |
Natural Killer (NK) cells are key actors of innate immunity that supervise the organism's cells, and fight against viral infections and cancer development through their cytotoxic activity. This cytotoxic activity is modulated by cytokines and hormones and could be influenced by physiological or pathological conditions. New techniques for measuring NK cytotoxic activity by flow-cytometry have recently been developed, and they correlated strongly with the standard chromium ((51)Cr) release assay. Our aim was to implement a previously published enhanced green fluorescent protein (EGFP)-K562 flow cytometric method and use it to evaluate NK cytotoxic activity under different nutritional conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1552-4922
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pubmed:author | |
pubmed:copyrightInfo |
(c) 2006 International Society for Analytical Cytology.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
992-8
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:16969797-Aged,
pubmed-meshheading:16969797-Cytotoxicity, Immunologic,
pubmed-meshheading:16969797-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:16969797-Eating,
pubmed-meshheading:16969797-Fasting,
pubmed-meshheading:16969797-Flow Cytometry,
pubmed-meshheading:16969797-Green Fluorescent Proteins,
pubmed-meshheading:16969797-Humans,
pubmed-meshheading:16969797-K562 Cells,
pubmed-meshheading:16969797-Killer Cells, Natural,
pubmed-meshheading:16969797-Male
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pubmed:year |
2006
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pubmed:articleTitle |
Implementation of the EGFP-K562 flow cytometric NK test: determination of NK cytotoxic activity in healthy elderly volunteers before and after feeding.
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pubmed:affiliation |
Laboratoire de Biochimie, Biologie Moléculaire et Nutrition EA2416, Faculté de Pharmacie, IFR 79 Santé-Auvergne, CLARA, Université Clermont 1, Clermont-Ferrand, France.
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pubmed:publicationType |
Journal Article
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