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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1990-9-27
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pubmed:abstractText |
The authors examined the localization and behavior of beta-human chorionic gonadotropin (HCG)-positive cells in human gastric noncancerous mucosa and in gastric malignant tumors, using immunohistochemistry and the anti-beta-HCG antibody. The beta-HCG-positive cells were located mainly in the antral mucosa and were generally restricted to the neck portion of the pyloric glands, although a few were present in fundic glands of the gastric body. The beta-HCG-immunoreactive cells were found in gastric carcinomas in 53% of the 92 cases examined. These cells were observed more often in advanced carcinomas that were histologically poorly differentiated than in early carcinomas or in well-differentiated tumors, but this prevalence had no statistical significance. The presence of the beta-HCG-positive cells in the gastric carcinomas suggested no appreciable prognostic significance, even quantitatively. In the syncytiotrophoblast-like tumor cells seen in four gastric tumor samples with histologic features of a choriocarcinoma, immunoreactivity to the beta-HCG was striking. There was, however, no recognizable dominance in the number of beta-HCG-reactive cells in the noncancerous mucosa around the tumor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
695-701
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1696845-Adenocarcinoma,
pubmed-meshheading:1696845-Choriocarcinoma,
pubmed-meshheading:1696845-Chorionic Gonadotropin,
pubmed-meshheading:1696845-Chorionic Gonadotropin, beta Subunit, Human,
pubmed-meshheading:1696845-Cytoplasm,
pubmed-meshheading:1696845-Female,
pubmed-meshheading:1696845-Gastric Fundus,
pubmed-meshheading:1696845-Gastric Mucosa,
pubmed-meshheading:1696845-Humans,
pubmed-meshheading:1696845-Immunohistochemistry,
pubmed-meshheading:1696845-Male,
pubmed-meshheading:1696845-Peptide Fragments,
pubmed-meshheading:1696845-Pyloric Antrum,
pubmed-meshheading:1696845-Reference Values,
pubmed-meshheading:1696845-Stomach Neoplasms
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pubmed:year |
1990
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pubmed:articleTitle |
Distribution of beta-human chorionic gonadotropin-positive cells in noncancerous gastric mucosa and in malignant gastric tumors.
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pubmed:affiliation |
Second Department of Pathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article
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