Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2006-10-2
pubmed:abstractText
Eukaryotic cells use an elaborate machinery involving the COPI coat complex to control protein trafficking in the secretory pathway. Although individual components of this complex are well known and their roles in deforming lipid membranes into coated carriers are well described, the precise sequence of molecular events by which these components assemble into and release from the COPI coat lattice remains unclear. Here, we present images and movies characterizing the dynamics of protein components of the COPI coat in living cells. We discuss the self-assembly of these coat components into a molecular machine for sorting and trafficking membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1879-3088
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
e1-4
pubmed:dateRevised
2008-8-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Insights into COPI coat assembly and function in living cells.
pubmed:affiliation
Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Building 18T Room 101, 18 Library Drive, Bethesda, MD 20892-5430, USA. jlippin@helix.nih.gov
pubmed:publicationType
Journal Article, Review