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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-9-5
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pubmed:abstractText |
Gene silencing via promoter hypermethylation is a central event in the pathogenesis of cancers. To identify novel methylation targets in colon cancer, we conducted a genome-wide, microarray-based, in silico, and epigenetic search.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:AbrahamJohn MJM,
pubmed-author:BerkiAgnes TAT,
pubmed-author:ChengYulanY,
pubmed-author:DAYN ENE,
pubmed-author:HamiltonJames PJP,
pubmed-author:ItoTetsuoT,
pubmed-author:KanTakatsuguT,
pubmed-author:MantzurCarmitC,
pubmed-author:MeltzerStephen JSJ,
pubmed-author:MoriYurikoY,
pubmed-author:PaunBogdanB,
pubmed-author:SatoFumiakiF,
pubmed-author:TanS FSF,
pubmed-author:WangSunaS
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
797-808
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16952549-Adult,
pubmed-meshheading:16952549-Aged,
pubmed-meshheading:16952549-Aged, 80 and over,
pubmed-meshheading:16952549-Colonic Neoplasms,
pubmed-meshheading:16952549-DNA, Neoplasm,
pubmed-meshheading:16952549-DNA Methylation,
pubmed-meshheading:16952549-Female,
pubmed-meshheading:16952549-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16952549-Gene Silencing,
pubmed-meshheading:16952549-Genome, Human,
pubmed-meshheading:16952549-Humans,
pubmed-meshheading:16952549-Male,
pubmed-meshheading:16952549-Microarray Analysis,
pubmed-meshheading:16952549-Microsatellite Repeats,
pubmed-meshheading:16952549-Middle Aged,
pubmed-meshheading:16952549-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16952549-Somatostatin,
pubmed-meshheading:16952549-Substance P
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pubmed:year |
2006
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pubmed:articleTitle |
A genome-wide search identifies epigenetic silencing of somatostatin, tachykinin-1, and 5 other genes in colon cancer.
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pubmed:affiliation |
Department of Medicine, Division of Gastroenterology, University of Maryland School of Medicine, Baltimore, Maryland, USA. ymori3@jhmi.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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