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rdf:type |
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lifeskim:mentions |
umls-concept:C0001443,
umls-concept:C0003873,
umls-concept:C0025677,
umls-concept:C0030705,
umls-concept:C0087111,
umls-concept:C0205419,
umls-concept:C0314603,
umls-concept:C0439849,
umls-concept:C1274040,
umls-concept:C1704259,
umls-concept:C1705987
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pubmed:issue |
9
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pubmed:dateCreated |
2006-10-2
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pubmed:abstractText |
Among patients with rheumatoid arthritis (RA), there is a high degree of interindividual variability in the degree of response to methotrexate (MTX) treatment. This study was undertaken to explore polymorphisms in genes contributing to antiinflammatory adenosine release as novel predictors of MTX treatment outcome.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:AllaartCornelia FCF,
pubmed-author:ColleeGerardG,
pubmed-author:De JongeRobertR,
pubmed-author:De SonnavillePeterP,
pubmed-author:De Vries-BouwstraJeska KJK,
pubmed-author:GuchelaarHenk-JanHJ,
pubmed-author:HuizingaTom W JTW,
pubmed-author:KooloosWouter MWM,
pubmed-author:LindemansJanJ,
pubmed-author:LinssenAnneliesA,
pubmed-author:WesselsJudith A MJA
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2830-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16947783-AMP Deaminase,
pubmed-meshheading:16947783-Adenosine,
pubmed-meshheading:16947783-Adult,
pubmed-meshheading:16947783-Aged,
pubmed-meshheading:16947783-Antirheumatic Agents,
pubmed-meshheading:16947783-Arthritis, Rheumatoid,
pubmed-meshheading:16947783-DNA,
pubmed-meshheading:16947783-Female,
pubmed-meshheading:16947783-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:16947783-Genetic Variation,
pubmed-meshheading:16947783-Humans,
pubmed-meshheading:16947783-Male,
pubmed-meshheading:16947783-Methotrexate,
pubmed-meshheading:16947783-Middle Aged,
pubmed-meshheading:16947783-Polymorphism, Single Nucleotide,
pubmed-meshheading:16947783-Single-Blind Method
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pubmed:year |
2006
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pubmed:articleTitle |
Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.
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pubmed:affiliation |
Leiden University Medical Center, Leiden, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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