Linked Life Data

16946187

Source:http://linkedlifedata.com/resource/pubmed/id/16946187

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2006-9-1
pubmed:abstractText
Altered patterns of brain activity during cognitive tasks have been demonstrated using functional magnetic resonance imaging (fMRI) in mild cognitive impairment and Alzheimer's disease. However, there have been few studies of adults at genetic risk for Alzheimer's disease prior to the onset of symptoms. The purpose of this study was to determine whether brain activation patterns associated with working memory differ as a function of apolipoprotein E (APOE) genotype in cognitively intact adults.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0002-953X
pubmed:author
pubmed:issnType
Print
pubmed:volume
163
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1603-10
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:16946187-Adult, pubmed-meshheading:16946187-Aged, pubmed-meshheading:16946187-Alleles, pubmed-meshheading:16946187-Alzheimer Disease, pubmed-meshheading:16946187-Apolipoprotein E3, pubmed-meshheading:16946187-Apolipoprotein E4, pubmed-meshheading:16946187-Apolipoproteins E, pubmed-meshheading:16946187-Brain, pubmed-meshheading:16946187-Cognition, pubmed-meshheading:16946187-Female, pubmed-meshheading:16946187-Functional Laterality, pubmed-meshheading:16946187-Genotype, pubmed-meshheading:16946187-Humans, pubmed-meshheading:16946187-Magnetic Resonance Imaging, pubmed-meshheading:16946187-Male, pubmed-meshheading:16946187-Memory, pubmed-meshheading:16946187-Neuropsychological Tests, pubmed-meshheading:16946187-Parietal Lobe, pubmed-meshheading:16946187-Prefrontal Cortex, pubmed-meshheading:16946187-Psychomotor Performance, pubmed-meshheading:16946187-Risk Factors, pubmed-meshheading:16946187-Task Performance and Analysis, pubmed-meshheading:16946187-Verbal Behavior
pubmed:year
2006
pubmed:articleTitle
Increased brain activation during working memory in cognitively intact adults with the APOE epsilon4 allele.
pubmed:affiliation
Neuropsychology Program and Brain Imaging Laboratory, Department of Psychiatry, Dartmouth Medical School/DHMC, One Medical Center Dr., Lebanon, NH 03756-0001, USA. wishart@dartmouth.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural