|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2007-3-6
|
|
pubmed:abstractText |
The concentration of cysteine protease inhibitor cystatin C was determined in sera from 59 patients with non-Hodgkin B-cell lymphoma using ELISA. The sera from 43 age and sex matched healthy blood donors served as controls. Cystatin C was significantly increased in sera of patients without therapy (mean 1136+/-SE 105.7ng/ml, p=0.00001) and with therapy (mean 1073+/-52ng/ml, p=0.001) compared to controls (mean 819+/-28ng/ml). The highest levels were determined in sera of patients with a relapse (mean 1680+/-196ng/ml). By using immunofluorescence staining and confocal microscopy we determined immature dendritic cells as a major population of cystatin C positive cells in affected lymph nodes. Our study reports for the first time that cystatin C is a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0304-3835
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
18
|
|
pubmed:volume |
248
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
192-7
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:16945481-Adolescent,
pubmed-meshheading:16945481-Adult,
pubmed-meshheading:16945481-Aged,
pubmed-meshheading:16945481-Aged, 80 and over,
pubmed-meshheading:16945481-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16945481-Creatinine,
pubmed-meshheading:16945481-Cystatin C,
pubmed-meshheading:16945481-Cystatins,
pubmed-meshheading:16945481-Dendritic Cells,
pubmed-meshheading:16945481-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16945481-Female,
pubmed-meshheading:16945481-Fluorescent Antibody Technique,
pubmed-meshheading:16945481-History, 17th Century,
pubmed-meshheading:16945481-Humans,
pubmed-meshheading:16945481-Immunotherapy,
pubmed-meshheading:16945481-Lymph Nodes,
pubmed-meshheading:16945481-Lymphoma, B-Cell,
pubmed-meshheading:16945481-Male,
pubmed-meshheading:16945481-Microscopy, Confocal,
pubmed-meshheading:16945481-Neoplasm Recurrence, Local,
pubmed-meshheading:16945481-Prognosis,
pubmed-meshheading:16945481-Tumor Markers, Biological
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Cystatin C as a potential marker for relapse in patients with non-Hodgkin B-cell lymphoma.
|
|
pubmed:affiliation |
Medical Faculty, University of Tuzla, Bosnia and Herzegovina.
|
|
pubmed:publicationType |
Journal Article,
Historical Article,
Research Support, Non-U.S. Gov't
|
