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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-8-21
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pubmed:abstractText |
Follicular lymphoma (FL) arising primarily in the skin has recently been proposed as a distinct entity on the basis of a low incidence of t(14;18)(q32;q21) and bcl-2 expression, with a very high percentage of patients surviving more than 5 years. However, cases of t(14;18)(q32;q21)-positive primary cutaneous FL (PCFL) and examples of t(14;18)(q32;q21)-negative FL at nodal and other extranodal sites, are well documented. The aim of this study was to test the hypothesis that there is a subtype of FL lacking t(14;18)(q32;q21), which preferentially involves certain sites but is not restricted by anatomical location.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0309-0167
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16918969-Adult,
pubmed-meshheading:16918969-Aged,
pubmed-meshheading:16918969-Aged, 80 and over,
pubmed-meshheading:16918969-Chromosome Aberrations,
pubmed-meshheading:16918969-Chromosomes, Human, Pair 14,
pubmed-meshheading:16918969-Chromosomes, Human, Pair 18,
pubmed-meshheading:16918969-Female,
pubmed-meshheading:16918969-Genes, bcl-2,
pubmed-meshheading:16918969-Humans,
pubmed-meshheading:16918969-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16918969-Lymphoma, Follicular,
pubmed-meshheading:16918969-Male,
pubmed-meshheading:16918969-Middle Aged,
pubmed-meshheading:16918969-Neprilysin,
pubmed-meshheading:16918969-Polymerase Chain Reaction,
pubmed-meshheading:16918969-Prognosis,
pubmed-meshheading:16918969-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:16918969-Survival Analysis,
pubmed-meshheading:16918969-Translocation, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
BCL2 gene abnormalities define distinct clinical subsets of follicular lymphoma.
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pubmed:affiliation |
Department of Pathology, Western General Hospital, Edinburgh, and Division of Pathology and Neuroscience, University of Dundee, UK. john.goodlad@luht.scot.nhs.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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