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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
15
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pubmed:dateCreated |
2006-8-10
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|
pubmed:abstractText |
To investigate the combined antitumor activity in mice of immunotoxin SS1P and Taxol. Methods: Immunodeficient mice were implanted with A431/K5 tumors expressing mesothelin. Established tumors were treated i.v. with immunotoxin SS1P alone, i.p. with Taxol alone, or with the two agents together. SS1P was radiolabeled with (111)In and used to study the effect of Taxol on its uptake by A431/K5 tumors.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Aug
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pubmed:issn |
1078-0432
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
4695-701
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pubmed:meshHeading |
pubmed-meshheading:16899620-Animals,
pubmed-meshheading:16899620-Antibodies, Monoclonal,
pubmed-meshheading:16899620-Antineoplastic Agents,
pubmed-meshheading:16899620-Carcinoma,
pubmed-meshheading:16899620-Cell Line, Tumor,
pubmed-meshheading:16899620-Cell Proliferation,
pubmed-meshheading:16899620-Combined Modality Therapy,
pubmed-meshheading:16899620-Disease Models, Animal,
pubmed-meshheading:16899620-Dose-Response Relationship, Drug,
pubmed-meshheading:16899620-Drug Synergism,
pubmed-meshheading:16899620-Humans,
pubmed-meshheading:16899620-Injections, Intraperitoneal,
pubmed-meshheading:16899620-Injections, Subcutaneous,
pubmed-meshheading:16899620-Mice,
pubmed-meshheading:16899620-Mice, Nude,
pubmed-meshheading:16899620-Paclitaxel,
pubmed-meshheading:16899620-Structure-Activity Relationship,
pubmed-meshheading:16899620-Xenograft Model Antitumor Assays
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pubmed:year |
2006
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|
pubmed:articleTitle |
Synergistic antitumor activity of taxol and immunotoxin SS1P in tumor-bearing mice.
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|
pubmed:affiliation |
Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-4264, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
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