Linked Life Data

16894899

Source:http://linkedlifedata.com/resource/pubmed/id/16894899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-8-9
pubmed:abstractText
Camptothecin is a strong anti-tumor compound isolated from Camptotheca acuminata. One of the most important way for the production of Camptothecin is by cell cultures of Camptotheca acuminata. The effect of Cu2+ on camptothecin accumulation in Camptotheca acuminata cell line was described in this paper. The results showed that the optimum CuCl2 concentration in B5 medium was 0.008 mg/mL, which increased camptothecin production for 30 times compare to the control while has no inhibitive effects on cell growth, at the same time, the peroxidase activity was increased and the anthocyanidin accumulation was inhibited. The promotive effects of Cu2+ on camptothecin accumulation in light was higher than that in dark.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1000-3061
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
624-8
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Effects of cu2+ on biosynthesis of camptothecin in cell cultures of Camptotheca acuminata].
pubmed:affiliation
Department of Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China. guqing2002@hotmail.com
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't