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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-8-21
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pubmed:abstractText |
Alternative polyadenylation is a widespread mechanism contributing to transcript diversity in eukaryotes. Over half of mammalian genes are alternatively polyadenylated. Our understanding of poly(A) site evolution is limited by the lack of a reliable identification of conserved, equivalent poly(A) sites among species. We introduce here a working definition of conserved poly(A) sites as sites that are both (i) properly aligned in human and mouse orthologous 3' untranslated regions (UTRs) and (ii) supported by EST or cDNA data in both species.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-10357856,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-10899149,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-11544195,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-12600277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-12730695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-12799354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-12819125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-14707178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15078858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15103394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15215342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15608159,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15647503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-15741508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-16024819,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-16030070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-16131587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-16195578,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-16356263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-7651822,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-8524291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16872498-9185563
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16872498-3' Untranslated Regions,
pubmed-meshheading:16872498-Alternative Splicing,
pubmed-meshheading:16872498-Animals,
pubmed-meshheading:16872498-Automatic Data Processing,
pubmed-meshheading:16872498-Conserved Sequence,
pubmed-meshheading:16872498-Efficiency,
pubmed-meshheading:16872498-Evolution, Molecular,
pubmed-meshheading:16872498-Expressed Sequence Tags,
pubmed-meshheading:16872498-Humans,
pubmed-meshheading:16872498-Mammals,
pubmed-meshheading:16872498-Mice,
pubmed-meshheading:16872498-Models, Theoretical,
pubmed-meshheading:16872498-Organ Specificity,
pubmed-meshheading:16872498-Poly A,
pubmed-meshheading:16872498-Polyadenylation,
pubmed-meshheading:16872498-RNA Processing, Post-Transcriptional,
pubmed-meshheading:16872498-Rats,
pubmed-meshheading:16872498-Tissue Distribution
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pubmed:year |
2006
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pubmed:articleTitle |
Conservation of alternative polyadenylation patterns in mammalian genes.
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pubmed:affiliation |
INSERM ERM 206, Université de la Méditerranée, Luminy Case 906, 13288 Marseille, Cedex 09, France. ara@tagc.univ-mrs.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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