| pubmed-article:16859513 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C1512505 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C0023689 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C0041538 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C0072980 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C1335831 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C2746052 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:16859513 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:16859513 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:16859513 | pubmed:dateCreated | 2007-1-16 | lld:pubmed |
| pubmed-article:16859513 | pubmed:abstractText | Loss of the cyclin-dependent kinase inhibitor p27 is associated with poor prognosis in breast cancer. The decrease in p27 levels is mainly the result of enhanced proteasome-dependent degradation mediated by its specific ubiquitin ligase subunit S phase kinase protein 2 (Skp2). The mammalian target of rapamycin (mTOR) is a downstream mediator in the phosphoinositol 3' kinase (PI3K)/Akt pathway that down-regulates p27 levels in breast cancer. Rapamycin was found to stabilize p27 levels in breast cancer, but whether this effect is mediated through changes in Skp2 expression is unknown. | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16859513 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16859513 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16859513 | pubmed:issn | 1465-542X | lld:pubmed |
| pubmed-article:16859513 | pubmed:author | pubmed-author:HershkoDan... | lld:pubmed |
| pubmed-article:16859513 | pubmed:author | pubmed-author:ShapiraMa'ani... | lld:pubmed |
| pubmed-article:16859513 | pubmed:author | pubmed-author:RosenbergTzur... | lld:pubmed |
| pubmed-article:16859513 | pubmed:author | pubmed-author:KakiashviliEl... | lld:pubmed |
| pubmed-article:16859513 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16859513 | pubmed:volume | 8 | lld:pubmed |
| pubmed-article:16859513 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16859513 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16859513 | pubmed:pagination | R46 | lld:pubmed |
| pubmed-article:16859513 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:meshHeading | pubmed-meshheading:16859513... | lld:pubmed |
| pubmed-article:16859513 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16859513 | pubmed:articleTitle | The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells. | lld:pubmed |
| pubmed-article:16859513 | pubmed:affiliation | Department of Surgery A, Rambam Medical Center, Haifa 31096, Israel. m_shapira@rambam.health.gov.il | lld:pubmed |
| pubmed-article:16859513 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16859513 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16859513 | lld:pubmed |
