To investigate the effect of iguratimod (T-614), a non-steroidal anti-inflammatory drug, on TNFalpha mRNA expression and TNFalpha production, and on the activity of nuclear factor-kappaB (NF-kappaB) in the rat alveolar macrophage cell line (NR8383) activated by LPS.
Center for New Drug Research and Development, Jiangsu Key Laboratory for Molecular Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing 210097, China.
