rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2006-7-17
|
pubmed:abstractText |
Cytokines are of major importance in periodontal disease progression. Interleukin-12 (IL-12) stimulates interferon-gamma production by T helper type 1 (Th1) cells while IL-18 induces Th1 responses when present with IL-12 but Th2 responses in the absence of IL-12. IL-1beta has been correlated with periodontal disease destruction. This study determined the local concentrations of these cytokines in sites of gingivitis and periodontitis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
D
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0902-0055
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
256-60
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16842511-Adult,
pubmed-meshheading:16842511-Aged,
pubmed-meshheading:16842511-Aged, 80 and over,
pubmed-meshheading:16842511-Disease Progression,
pubmed-meshheading:16842511-Female,
pubmed-meshheading:16842511-Gingival Crevicular Fluid,
pubmed-meshheading:16842511-Gingivitis,
pubmed-meshheading:16842511-Humans,
pubmed-meshheading:16842511-Interleukin-1,
pubmed-meshheading:16842511-Interleukin-12,
pubmed-meshheading:16842511-Interleukin-12 Subunit p40,
pubmed-meshheading:16842511-Interleukin-18,
pubmed-meshheading:16842511-Male,
pubmed-meshheading:16842511-Middle Aged,
pubmed-meshheading:16842511-Periodontitis,
pubmed-meshheading:16842511-Protein Subunits,
pubmed-meshheading:16842511-Th1 Cells,
pubmed-meshheading:16842511-Th2 Cells
|
pubmed:year |
2006
|
pubmed:articleTitle |
Interleukin-1beta, interleukin-12 and interleukin-18 levels in gingival fluid and serum of patients with gingivitis and periodontitis.
|
pubmed:affiliation |
School of Dentistry, Brisbane, Qld, Australia. s4074382@student.uq.edu.au
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|