Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-7-18
pubmed:abstractText
Lasofoxifene, a new selective estrogen-receptor modulator (SERM), shows efficacy in vaginal and vulvar atrophy in postmenopausal women. Here, we sought to explore the possible mechanisms of action for this effect in comparison with other SERMs using an immature ovariectomized rat model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1072-3714
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
609-20
pubmed:meshHeading
pubmed-meshheading:16837883-Administration, Oral, pubmed-meshheading:16837883-Animals, pubmed-meshheading:16837883-Atrophy, pubmed-meshheading:16837883-Disease Models, Animal, pubmed-meshheading:16837883-Dose-Response Relationship, Drug, pubmed-meshheading:16837883-Estrogen Receptor beta, pubmed-meshheading:16837883-Ethinyl Estradiol, pubmed-meshheading:16837883-Female, pubmed-meshheading:16837883-Mucous Membrane, pubmed-meshheading:16837883-Ovariectomy, pubmed-meshheading:16837883-Postmenopause, pubmed-meshheading:16837883-Pyrrolidines, pubmed-meshheading:16837883-Raloxifene, pubmed-meshheading:16837883-Rats, pubmed-meshheading:16837883-Rats, Sprague-Dawley, pubmed-meshheading:16837883-Receptors, Androgen, pubmed-meshheading:16837883-Selective Estrogen Receptor Modulators, pubmed-meshheading:16837883-Tamoxifen, pubmed-meshheading:16837883-Tetrahydronaphthalenes, pubmed-meshheading:16837883-Uterus, pubmed-meshheading:16837883-Vagina, pubmed-meshheading:16837883-Vaginal Diseases
pubmed:articleTitle
Lasofoxifene enhances vaginal mucus formation without causing hypertrophy and increases estrogen receptor beta and androgen receptor in rats.
pubmed:affiliation
Pfizer Global Research and Development, Pfizer, Inc, Groton, CT 06340, USA. xiao.n.wang@pfizer.com
pubmed:publicationType
Journal Article