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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-7-11
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pubmed:abstractText |
Release of 5-hydroxytryptamine (5-HT) from mucosal enterochromaffin cells and activation of 5-HT(3) receptors (5-HT(3)Rs) on neurons in the gut wall is important in the response of the gut to the luminal environment. Intestinal inflammation is associated with increased levels of mucosal 5-HT. The aims of the study were to determine the following: (1) if 5-HT(3)R undergoes ligand-induced internalization in myenteric neurons, and (2) the effect of long-term increase of mucosal 5-HT on 5-HT(3)Rs.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-107
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16831594-Animals,
pubmed-meshheading:16831594-Blotting, Western,
pubmed-meshheading:16831594-Fluoxetine,
pubmed-meshheading:16831594-Ileum,
pubmed-meshheading:16831594-Immunohistochemistry,
pubmed-meshheading:16831594-Intestinal Absorption,
pubmed-meshheading:16831594-Intestinal Mucosa,
pubmed-meshheading:16831594-Male,
pubmed-meshheading:16831594-Myenteric Plexus,
pubmed-meshheading:16831594-Neurons,
pubmed-meshheading:16831594-Ondansetron,
pubmed-meshheading:16831594-Rats,
pubmed-meshheading:16831594-Rats, Sprague-Dawley,
pubmed-meshheading:16831594-Receptors, Serotonin, 5-HT3,
pubmed-meshheading:16831594-Serotonin Antagonists,
pubmed-meshheading:16831594-Serotonin Uptake Inhibitors
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pubmed:year |
2006
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pubmed:articleTitle |
Ligand-induced 5-HT3 receptor internalization in enteric neurons in rat ileum.
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pubmed:affiliation |
Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, 95616, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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