rdf:type |
|
lifeskim:mentions |
umls-concept:C0007589,
umls-concept:C0007600,
umls-concept:C0010453,
umls-concept:C0014834,
umls-concept:C0017262,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0243039,
umls-concept:C0282639,
umls-concept:C0475264,
umls-concept:C0597357,
umls-concept:C0699790,
umls-concept:C1511938,
umls-concept:C1518174,
umls-concept:C1524063,
umls-concept:C1998793,
umls-concept:C2603343,
umls-concept:C2911684
|
pubmed:issue |
11
|
pubmed:dateCreated |
1991-11-27
|
pubmed:abstractText |
Whole diffusely adhering Escherichia coli (DAEC) C1845 cells bearing the F1845 adhesive factor bind diffusely to differentiated human colon carcinoma cell lines HT-29 and Caco-2. By using antibodies directed against the purified fimbrial adhesin F1845 factor, the expression of the DAEC F1845-specific brush border receptors in the polarized human intestinal HT-29 and Caco-2 epithelial cells was studied by indirect immunofluorescence. A low level of DAEC F1845 receptors in undifferentiated intestinal cells was detected; they were localized in a cluster of cells. DAEC F1845 receptors were expressed at a high level in differentiated HT-29 and Caco-2 cells. DAEC F1845 receptors were expressed at a strikingly high level in the apical domains of the cells and developed during enterocytic differentiation in culture, in parallel with the apical expression of the intestinal brush border hydrolase, sucrase-isomaltase.
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-1100526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-1967170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-1969827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-1969849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-1995723,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2108086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2172966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2180823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2205582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2230233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2230236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2311122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2364431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2404872,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2565291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2568985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2572550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2643705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2647635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2656874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2659527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2668429,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2680979,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2880484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2899125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-2902011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3052090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3054548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3117693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-327080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3516874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3539808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3548768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3897250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-3939606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-6132875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-6143731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-6146569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-6342499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1682255-80383
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0019-9567
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
59
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4013-8
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:1682255-Bacterial Adhesion,
pubmed-meshheading:1682255-Cell Differentiation,
pubmed-meshheading:1682255-Cell Membrane,
pubmed-meshheading:1682255-Colon,
pubmed-meshheading:1682255-Escherichia coli,
pubmed-meshheading:1682255-Fimbriae, Bacterial,
pubmed-meshheading:1682255-Humans,
pubmed-meshheading:1682255-Protein Binding,
pubmed-meshheading:1682255-Receptors, Immunologic,
pubmed-meshheading:1682255-Tumor Cells, Cultured
|
pubmed:year |
1991
|
pubmed:articleTitle |
Use of purified F1845 fimbrial adhesin to study localization and expression of receptors for diffusely adhering Escherichia coli during enterocytic differentiation of human colon carcinoma cell lines HT-29 and Caco-2 in culture.
|
pubmed:affiliation |
Département de Microbiologie et Immunologie, UFR Sciences Pharmaceutiques Paris XI, Châtenay-Malabry, France.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|