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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1991-11-4
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pubmed:abstractText |
Serum angiotensin-converting enzyme (ACE) activity was measured in 70 middle-aged male drinkers with or without elevated serum gamma-glutamyl transpeptidase (gamma-GTP) activity and high BP. Serum ACE activity in hypertensive drinkers with elevated serum gamma-GTP was higher than that in drinkers, both normotensive and hypertensive, with normal serum gamma-GTP. Serum ACE levels were strongly correlated with alcohol consumption and serum gamma-GTP levels. Since the induction of ACE by alcohol in hepatic cells has been disputed, the coincident elevation of serum ACE and gamma-GTP activities in hypertensive drinkers may support the contention that the close association between gamma-GTP levels and BP found in drinkers is not mainly related to the induction of gamma-GTP in the hepatic cells, but related to the hepatic cell damage caused by alcohol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0950-9240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
183-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1681104-Adult,
pubmed-meshheading:1681104-Alcohol Drinking,
pubmed-meshheading:1681104-Humans,
pubmed-meshheading:1681104-Hypertension,
pubmed-meshheading:1681104-Male,
pubmed-meshheading:1681104-Middle Aged,
pubmed-meshheading:1681104-Peptidyl-Dipeptidase A,
pubmed-meshheading:1681104-gamma-Glutamyltransferase
|
pubmed:year |
1991
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pubmed:articleTitle |
Elevations of serum angiotensin-converting enzyme and gamma-glutamyl transpeptidase activities in hypertensive drinkers.
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pubmed:affiliation |
Department of Hygiene, Kanazawa Medical University, Ishikawa, Japan.
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pubmed:publicationType |
Journal Article
|