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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1991-10-2
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pubmed:abstractText |
In situ hybridization was performed in the rat brain to detect aromatic L-amino acid decarboxylase (AADC) mRNA using 35S-labeled oligonucleotide probes derived from rat kidney AADC cDNA. Results demonstrated AADC mRNA in areas containing dopaminergic and serotoninergic cell bodies. Combined immunohistochemistry for tyrosine- or tryptophan hydroxylase and in situ hybridization for AADC mRNA demonstrated the dopaminergic or serotoninergic nature of cells containing AADC mRNA. Tyrosine hydroxylase-positive mesencephalic neurons containing a very low or no AADC mRNA signal were also observed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0304-3940
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
203-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1679228-5-Hydroxytryptophan,
pubmed-meshheading:1679228-Amino Acid Sequence,
pubmed-meshheading:1679228-Animals,
pubmed-meshheading:1679228-Aromatic-L-Amino-Acid Decarboxylases,
pubmed-meshheading:1679228-Brain Stem,
pubmed-meshheading:1679228-Gene Expression,
pubmed-meshheading:1679228-Levodopa,
pubmed-meshheading:1679228-Male,
pubmed-meshheading:1679228-Molecular Sequence Data,
pubmed-meshheading:1679228-Neurons,
pubmed-meshheading:1679228-RNA, Messenger,
pubmed-meshheading:1679228-Rats,
pubmed-meshheading:1679228-Rats, Inbred Strains,
pubmed-meshheading:1679228-Tryptophan Hydroxylase,
pubmed-meshheading:1679228-Tyrosine 3-Monooxygenase
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pubmed:year |
1991
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pubmed:articleTitle |
Aromatic L-amino-acid decarboxylase (DOPA decarboxylase) gene expression in dopaminergic and serotoninergic cells of the rat brainstem.
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pubmed:affiliation |
URA CNRS 1200 Laboratoire d'Histologie-Embryologie, Université de Bordeaux II, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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