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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-7-19
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pubmed:abstractText |
Epidemiological and experimental studies support a link between genetic and epigenetic factors in vulnerability to develop enduring neurobehavioral alterations. We studied the interplay between genetic vulnerability and the prenatal exposure to a neurotoxic compound. Chlorpyrifos, a potent and reversible acetylcholinesterase blocker used as a pesticide, and the "reeler" mouse, lacking the extracellular-matrix protein Reelin, were used.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amphetamine,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules, Neuronal,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorpyrifos,
http://linkedlifedata.com/resource/pubmed/chemical/Cholinesterase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Matrix Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/O,O-diethyl...,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/reelin protein
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0033-3158
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
187
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
331-44
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pubmed:meshHeading |
pubmed-meshheading:16783542-Amphetamine,
pubmed-meshheading:16783542-Animals,
pubmed-meshheading:16783542-Behavior, Animal,
pubmed-meshheading:16783542-Brain,
pubmed-meshheading:16783542-Cell Adhesion Molecules, Neuronal,
pubmed-meshheading:16783542-Chlorpyrifos,
pubmed-meshheading:16783542-Cholinesterase Inhibitors,
pubmed-meshheading:16783542-Extracellular Matrix Proteins,
pubmed-meshheading:16783542-Female,
pubmed-meshheading:16783542-Fetus,
pubmed-meshheading:16783542-Growth,
pubmed-meshheading:16783542-Male,
pubmed-meshheading:16783542-Mice,
pubmed-meshheading:16783542-Mice, Neurologic Mutants,
pubmed-meshheading:16783542-Motor Activity,
pubmed-meshheading:16783542-Nerve Tissue Proteins,
pubmed-meshheading:16783542-Reflex,
pubmed-meshheading:16783542-Serine Endopeptidases,
pubmed-meshheading:16783542-Stereotyped Behavior,
pubmed-meshheading:16783542-Vocalization, Animal
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pubmed:year |
2006
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pubmed:articleTitle |
Paradoxical effects of prenatal acetylcholinesterase blockade on neuro-behavioral development and drug-induced stereotypies in reeler mutant mice.
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pubmed:affiliation |
Behavioural Neuroscience, Department of Cell Biology and Neurosciences, Istituto Superiore di Sanita', viale Regina Elena 299, 00161, Rome, Italy. laviola@iss.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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