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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1991-9-17
|
| pubmed:abstractText |
1. A dose-response relationship between intraduodenal perfusion of different HCl loads (1.8, 4.5, 9, 18 and 45 mmol/hr) and volume, bicarbonate and protein outputs, from the exocrine pancreas of anaesthetized rabbits was observed. 2. This study also shows a dose-response relationship between the different HCl loads and the porta levels of secretin and VIP. 3. The secretin response showed a marked decrease during the stimulation period and this may suggest the involvement of a neural mechanism. 4. The plasma VIP responses were of a magnitude that might suggest a hormone role for VIP in this effect.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0300-9629
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
99
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
313-21
|
| pubmed:dateRevised |
2008-10-30
|
| pubmed:meshHeading |
pubmed-meshheading:1678329-Animals,
pubmed-meshheading:1678329-Dose-Response Relationship, Drug,
pubmed-meshheading:1678329-Duodenum,
pubmed-meshheading:1678329-Hydrochloric Acid,
pubmed-meshheading:1678329-Hydrogen-Ion Concentration,
pubmed-meshheading:1678329-Infusion Pumps,
pubmed-meshheading:1678329-Male,
pubmed-meshheading:1678329-Pancreas,
pubmed-meshheading:1678329-Rabbits,
pubmed-meshheading:1678329-Secretin,
pubmed-meshheading:1678329-Vasoactive Intestinal Peptide
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Pancreatic dose dependent effect of intraduodenal HCl in the anesthetized rabbit.
|
| pubmed:affiliation |
Departamento de Fisiologia y Farmacología, Universidad de Salamanca, Spain.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|