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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2006-6-13
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pubmed:abstractText |
Recent reports suggest that mesenchymal stem cells (MSCs) have immunomodulatory properties. Mesenchymal stem cells can suppress the immune response toward alloantigen in vitro by inhibiting T cell proliferation in mixed-lymphocyte reactions (MLRs). However, relatively little has been reported regarding the immunomodulative potential of MSCs in vivo. Herein the authors confirm the immunomodulatory effects of rat MSCs in vitro and tested for tolerogenic features in a model of allogeneic heart transplantation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1589-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16770249-Adipocytes,
pubmed-meshheading:16770249-Animals,
pubmed-meshheading:16770249-Cell Differentiation,
pubmed-meshheading:16770249-Cells, Cultured,
pubmed-meshheading:16770249-Cyclosporine,
pubmed-meshheading:16770249-Graft Rejection,
pubmed-meshheading:16770249-Heart Transplantation,
pubmed-meshheading:16770249-Histocompatibility Antigens Class I,
pubmed-meshheading:16770249-Immunosuppressive Agents,
pubmed-meshheading:16770249-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:16770249-Male,
pubmed-meshheading:16770249-Mesenchymal Stem Cells,
pubmed-meshheading:16770249-Rats,
pubmed-meshheading:16770249-Rats, Inbred ACI,
pubmed-meshheading:16770249-Rats, Inbred Lew,
pubmed-meshheading:16770249-Spleen,
pubmed-meshheading:16770249-T-Lymphocytes,
pubmed-meshheading:16770249-Transplantation, Homologous,
pubmed-meshheading:16770249-Transplantation Tolerance
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pubmed:year |
2006
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pubmed:articleTitle |
Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant model.
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pubmed:affiliation |
Department of Surgery, University of Regensburg, Regensburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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