Source:http://linkedlifedata.com/resource/pubmed/id/16764966
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-7-24
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pubmed:abstractText |
Along with reproductive success and predation, infectious disease is a major demographic and evolutionary driver of natural populations. To understand the evolutionary impacts of disease, research has focussed on the major histocompatibility complex (MHC), a genetic region involved in antigen presentation. There is a pressing need for the broader research currently conducted on traditional vertebrate models to be transferred to wildlife. Incorporating such knowledge will enable a broader understanding of the levels at which natural selection can act on immunity. We propose two new approaches to wildlife immunogenetics and discuss the challenges of conducting such studies. At a time when novel pathogens are increasingly emerging in natural populations, these new approaches are integral to understanding disease dynamics and assessing epidemic risks.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0169-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
433-8
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pubmed:dateRevised |
2011-5-3
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pubmed:meshHeading | |
pubmed:year |
2006
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pubmed:articleTitle |
Is MHC enough for understanding wildlife immunogenetics?
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pubmed:affiliation |
Institute of Zoology, Regent's Park, London, NW1 4RY, UK. karina.acevedo-whitehouse@ioz.ac.uk
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pubmed:publicationType |
Journal Article
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