Linked Life Data

16762428

Source:http://linkedlifedata.com/resource/pubmed/id/16762428

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5-6
pubmed:dateCreated
2006-7-11
pubmed:abstractText
Apoptosis is a form of programmed cell death that is essential for the development and tissue homeostasis in all metazoan animals. Mitochondria play a critical role during apoptosis, since the release of pro-apoptogenic proteins from the organelle is a pivotal event in cell death triggered by many cytotoxic stimuli. A striking morphological change occurring during apoptosis is the disintegration of the semi-reticular mitochondrial network into small punctiform organelles. It is only recently that this event has been shown to require the activity of proteins involved in the physiological processes of mitochondrial fission and fusion. Here, we discuss how this mitochondrial morphological transition occurs during cell death and the role that it may have in apoptosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0006-3002
pubmed:author
pubmed:issnType
Print
pubmed:volume
1763
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
522-30
pubmed:meshHeading
pubmed:articleTitle
Mitochondrial fission and apoptosis: an ongoing trial.
pubmed:affiliation
Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.
pubmed:publicationType
Journal Article, Review