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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-8-8
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pubmed:abstractText |
The type 1 IGF-I receptor (IGF1R) mediates the biological functions of IGF-I. Binding of IGF-I to the IGF1R results in autophosphorylation of the intracellular beta-subunit and activation of intracellular signaling.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3062-70
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16757531-Adult,
pubmed-meshheading:16757531-Base Sequence,
pubmed-meshheading:16757531-Body Height,
pubmed-meshheading:16757531-Bone Density,
pubmed-meshheading:16757531-DNA, Complementary,
pubmed-meshheading:16757531-DNA Mutational Analysis,
pubmed-meshheading:16757531-Failure to Thrive,
pubmed-meshheading:16757531-Female,
pubmed-meshheading:16757531-Fetal Growth Retardation,
pubmed-meshheading:16757531-Fibroblasts,
pubmed-meshheading:16757531-Glutamic Acid,
pubmed-meshheading:16757531-Growth Disorders,
pubmed-meshheading:16757531-Heterozygote,
pubmed-meshheading:16757531-Humans,
pubmed-meshheading:16757531-Infant,
pubmed-meshheading:16757531-Insulin-Like Growth Factor I,
pubmed-meshheading:16757531-Lysine,
pubmed-meshheading:16757531-Microcephaly,
pubmed-meshheading:16757531-Mutation, Missense,
pubmed-meshheading:16757531-Phosphorylation,
pubmed-meshheading:16757531-Polymerase Chain Reaction,
pubmed-meshheading:16757531-Receptor, IGF Type 1,
pubmed-meshheading:16757531-Sequence Analysis, DNA,
pubmed-meshheading:16757531-Signal Transduction
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pubmed:year |
2006
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pubmed:articleTitle |
A variable degree of intrauterine and postnatal growth retardation in a family with a missense mutation in the insulin-like growth factor I receptor.
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pubmed:affiliation |
Department of Pediatrics J6-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands. m.j.e.walenkamp@lumc.nl
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pubmed:publicationType |
Journal Article,
Case Reports
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