rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2006-6-5
|
pubmed:abstractText |
There is accumulating evidence that cancer patients with human immmunodeficiency virus-1/acquired immunodeficency syndrome (HIV-1/AIDS) have more severe tissue reactions and often develop cutaneous toxic effects when subjected to radiotherapy. Here we explored the effects of the HIV-1 Tat protein on cellular responses to ionizing radiation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0360-3016
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
65
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
842-50
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:16751065-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:16751065-Cell Line,
pubmed-meshheading:16751065-Cell Proliferation,
pubmed-meshheading:16751065-Comet Assay,
pubmed-meshheading:16751065-DNA Damage,
pubmed-meshheading:16751065-DNA Repair,
pubmed-meshheading:16751065-DNA-Activated Protein Kinase,
pubmed-meshheading:16751065-G2 Phase,
pubmed-meshheading:16751065-Gene Expression,
pubmed-meshheading:16751065-Gene Products, tat,
pubmed-meshheading:16751065-HIV-1,
pubmed-meshheading:16751065-Humans,
pubmed-meshheading:16751065-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16751065-Radiation Tolerance,
pubmed-meshheading:16751065-tat Gene Products, Human Immunodeficiency Virus
|
pubmed:year |
2006
|
pubmed:articleTitle |
HIV-1 Tat depresses DNA-PK(CS) expression and DNA repair, and sensitizes cells to ionizing radiation.
|
pubmed:affiliation |
Department of Radiation Toxicology and Oncology, Beijing Institute of Radiation Medicine, Beijing, People's Republic of China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|