Source:http://linkedlifedata.com/resource/pubmed/id/16730172
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
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pubmed:dateCreated |
2006-6-20
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pubmed:abstractText |
The structural similarity between beta-lactam antibiotics, such as penicillin, and isoxazolidine-3,5-dicarboxylic acids led to the hypothesis that isoxazolidine-3,5-dicarboxylic acids could be effective analogs of beta-lactam antibiotics. The syntheses of relevant isoxazolidine-3,5-dicarboxylic acids from acylnitroso Diels-Alder adducts and subsequent biological testing have shown that these first examples are inhibitors of Escherichia coli X580.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3966-70
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
2006
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pubmed:articleTitle |
The synthesis and in vitro testing of structurally novel antibiotics derived from acylnitroso Diels-Alder adducts.
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pubmed:affiliation |
Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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