Source:http://linkedlifedata.com/resource/pubmed/id/16719450
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
21
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| pubmed:dateCreated |
2006-5-24
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| pubmed:abstractText |
Cu(II)-catalyzed acetoxylation and halogenation of aryl C-H bonds are developed. ortho-Selectivity was observed with a wide range of 2-arylpyridine substrates. Both mono- and difunctionalizations are achieved by tuning the reaction conditions. Excellent functional group tolerance and use of O2 as a stoichiometric oxidant are significant advantages over our recently developed Pd-catalyzed C-H functionalization reactions. These newly discovered reaction conditions are also applicable for cyanation, amination, etherification, and thioetherification of aryl C-H bonds. Mechanistic investigations are carried out to gain insights into the Cu(II)-catalyzed C-H functionalization reactions.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
May
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| pubmed:issn |
0002-7863
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
31
|
| pubmed:volume |
128
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
6790-1
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| pubmed:dateRevised |
2008-1-17
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| pubmed:year |
2006
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| pubmed:articleTitle |
Cu(II)-catalyzed functionalizations of aryl C-H bonds using O2 as an oxidant.
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| pubmed:affiliation |
Department of Chemistry MS015, Brandeis University, Waltham, MA 02454-9110, USA.
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| pubmed:publicationType |
Journal Article
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