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pubmed-article:16714603pubmed:abstractTextWe isolated a human monoclonal antibody against diphtheria toxin (DT). It bound to fragment B with a binding activity (Kd) of 3.01 nM. The neutralizing activity assayed by the rabbit skin test was estimated to be 73,600 IU/g. This could be used as a therapeutic drug against DT in place of the traditional equine sera.lld:pubmed
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pubmed-article:16714603pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:16714603pubmed:articleTitleIsolation of a human monoclonal antibody with strong neutralizing activity against diphtheria toxin.lld:pubmed
pubmed-article:16714603pubmed:affiliationInstitute for Antibodies Ltd., Toyoake, Aichi 470-1192, Japan.lld:pubmed
pubmed-article:16714603pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16714603pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed