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rdf:type |
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lifeskim:mentions |
umls-concept:C0010819,
umls-concept:C0030705,
umls-concept:C0035696,
umls-concept:C0086418,
umls-concept:C0179445,
umls-concept:C0370003,
umls-concept:C0378279,
umls-concept:C0740277,
umls-concept:C1415670,
umls-concept:C1511790,
umls-concept:C1546566,
umls-concept:C1706090
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pubmed:issue |
6
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pubmed:dateCreated |
2006-6-27
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pubmed:abstractText |
The diagnosis of bile duct cancer is hampered by the low sensitivity of intraductal brush cytology and forceps biopsy. In the present study real-time reverse transcription polymerase chain reaction (RT-PCR) assays for the detection of human aspartyl (asparaginyl) beta-hydroxylase (HAAH) and homeobox B7 (HoxB7) mRNA from intraductal brush cytology specimens were established. Both markers are overexpressed in biliary cancer cell lines and possibly involved in the pathogenesis of bile duct cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0013-726X
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pubmed:author |
pubmed-author:AhlenstielGG,
pubmed-author:DumoulinF LFL,
pubmed-author:FeldmannGG,
pubmed-author:GerhardsUU,
pubmed-author:GorschlüterMM,
pubmed-author:KuntzenTT,
pubmed-author:NattermannJJ,
pubmed-author:NischalkeH DHD,
pubmed-author:SauerbruchTT,
pubmed-author:SpenglerUU,
pubmed-author:WolffMM
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
604-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16673309-Adult,
pubmed-meshheading:16673309-Aged,
pubmed-meshheading:16673309-Aged, 80 and over,
pubmed-meshheading:16673309-Bile Duct Neoplasms,
pubmed-meshheading:16673309-Bile Ducts, Intrahepatic,
pubmed-meshheading:16673309-Cell Line, Tumor,
pubmed-meshheading:16673309-Cholangiocarcinoma,
pubmed-meshheading:16673309-Female,
pubmed-meshheading:16673309-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16673309-Homeodomain Proteins,
pubmed-meshheading:16673309-Humans,
pubmed-meshheading:16673309-Male,
pubmed-meshheading:16673309-Middle Aged,
pubmed-meshheading:16673309-Mixed Function Oxygenases,
pubmed-meshheading:16673309-RNA, Messenger,
pubmed-meshheading:16673309-Reproducibility of Results,
pubmed-meshheading:16673309-Retrospective Studies,
pubmed-meshheading:16673309-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2006
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pubmed:articleTitle |
Detection of human aspartyl (asparaginyl) beta-hydroxylase and homeobox B7 mRNA in brush cytology specimens from patients with bile duct cancer.
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pubmed:affiliation |
Deparment of Internal Medicine 1, University of Bonn, Germany. gfeldma4@jhmi.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Validation Studies
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