Source:http://linkedlifedata.com/resource/pubmed/id/16671056
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2006-8-22
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pubmed:abstractText |
Neurotensin(8-13) analogs containing a glycine or 5-aminovaleroyl spacer were labeled with fluorescein through formation of an N-terminal thiourea function. The receptor binding was measured in HT-29 cell cultures and showed a substantial decrease in affinity, especially for the metabolically stabilized [MeArg(9), Tle(11)] analog. Using fluorescence microscopy, the internalization of the fluorescent neurotensin analogs into HT-29 cells was observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1075-2617
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2006 European Peptide Society and John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
505-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16671056-Fluorescein-5-isothiocyanate,
pubmed-meshheading:16671056-Fluorescent Dyes,
pubmed-meshheading:16671056-HT29 Cells,
pubmed-meshheading:16671056-Humans,
pubmed-meshheading:16671056-Microscopy, Fluorescence,
pubmed-meshheading:16671056-Molecular Structure,
pubmed-meshheading:16671056-Neurotensin,
pubmed-meshheading:16671056-Protein Binding,
pubmed-meshheading:16671056-Protein Transport,
pubmed-meshheading:16671056-Receptors, Neurotensin
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pubmed:year |
2006
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pubmed:articleTitle |
Fluorescein-labeled stable neurotensin derivatives.
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pubmed:affiliation |
Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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