Source:http://linkedlifedata.com/resource/pubmed/id/16647564
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-5-1
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pubmed:abstractText |
Lentiviral vectors are increasingly used for preclinical models of gene therapy and other forms of experimental transgenesis. Due to the broad tropism and the ability for concentration by ultracentrifugation, most lentiviral vector preparations are produced using the vesicular stomatitis virus glycoprotein (VSV-g) protein as envelope. Recently, Hanawa and colleagues have demonstrated that the ecotropic envelope protein of murine leukemia viruses allows efficient pseudotyping of HIV-1-derived vector particles. However, this method has found little acceptance, despite potential advantages.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0301-472X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
588-92
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16647564-Animals,
pubmed-meshheading:16647564-Base Sequence,
pubmed-meshheading:16647564-DNA Primers,
pubmed-meshheading:16647564-Gene Therapy,
pubmed-meshheading:16647564-Genetic Vectors,
pubmed-meshheading:16647564-Lentivirus,
pubmed-meshheading:16647564-Leukemia Virus, Murine,
pubmed-meshheading:16647564-Mice,
pubmed-meshheading:16647564-Polymerase Chain Reaction
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pubmed:year |
2006
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pubmed:articleTitle |
Lentiviral vectors pseudotyped with murine ecotropic envelope: increased biosafety and convenience in preclinical research.
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pubmed:affiliation |
Department of Hematology, Hemostaseology and Oncology, Hannover Medical School, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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