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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2006-5-15
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pubmed:abstractText |
Because of its dramatic public health impact, Plasmodium falciparum resistance to chloroquine (CQ) has been documented early on. Chloroquine-resistance (CQR) emerged in the late 1950's independently in South East Asia and South America and progressively spread over all malaria areas. CQR was reported in East Africa in the 1970's, and has since invaded the African continent. Many questions remain about the actual selection and spreading process of CQR parasites, and about the evolution of the ancestral mutant gene(s) during spreading.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-11090624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-11675500,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-11865433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-12124623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-12232841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-12499174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-12792863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-12797980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-14519577,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-15287598,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-15866507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-7790466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-8525414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16638153-9256492
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1475-2875
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pubmed:author |
pubmed-author:ArieyFrédéricF,
pubmed-author:BouchierChristianeC,
pubmed-author:CojeanSandrineS,
pubmed-author:DucheminJean BernardJB,
pubmed-author:DurandRemyR,
pubmed-author:EkalaMarie ThérèseMT,
pubmed-author:FandeurThierryT,
pubmed-author:JambouRonanR,
pubmed-author:Le BrasJacquesJ,
pubmed-author:LegrandEricE,
pubmed-author:Mercereau-PuijalonOdileO,
pubmed-author:RandrianarivelojosiaMilijaonaM,
pubmed-author:RobertVincentV
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16638153-Africa,
pubmed-meshheading:16638153-Alleles,
pubmed-meshheading:16638153-Animals,
pubmed-meshheading:16638153-Antimalarials,
pubmed-meshheading:16638153-Base Sequence,
pubmed-meshheading:16638153-Cambodia,
pubmed-meshheading:16638153-Chloroquine,
pubmed-meshheading:16638153-DNA, Protozoan,
pubmed-meshheading:16638153-Drug Resistance,
pubmed-meshheading:16638153-Haplotypes,
pubmed-meshheading:16638153-Humans,
pubmed-meshheading:16638153-Malaria, Falciparum,
pubmed-meshheading:16638153-Membrane Proteins,
pubmed-meshheading:16638153-Membrane Transport Proteins,
pubmed-meshheading:16638153-Microsatellite Repeats,
pubmed-meshheading:16638153-Molecular Sequence Data,
pubmed-meshheading:16638153-Plasmodium falciparum,
pubmed-meshheading:16638153-Protozoan Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
Invasion of Africa by a single pfcrt allele of South East Asian type.
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pubmed:affiliation |
Institut Pasteur du Cambodge, Phnom-Penh, Cambodia. fariey@pasteur-kh.org
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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