rdf:type |
|
lifeskim:mentions |
umls-concept:C0007113,
umls-concept:C0016360,
umls-concept:C0030705,
umls-concept:C0069717,
umls-concept:C0205179,
umls-concept:C0205390,
umls-concept:C0445204,
umls-concept:C1516238,
umls-concept:C1517033,
umls-concept:C1517927,
umls-concept:C1522449,
umls-concept:C2603343
|
pubmed:issue |
16
|
pubmed:dateCreated |
2006-5-31
|
pubmed:abstractText |
The addition of oxaliplatin to fluorouracil in patients with advanced colorectal cancer improves survival. This phase I/II study evaluated the addition of weekly oxaliplatin to preoperative continuous infusion fluorouracil (FU) and external-beam radiation therapy (RT) in patients with locally advanced rectal adenocarcinoma.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1527-7755
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2557-62
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:16636336-Adenocarcinoma,
pubmed-meshheading:16636336-Adult,
pubmed-meshheading:16636336-Aged,
pubmed-meshheading:16636336-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16636336-Chemotherapy, Adjuvant,
pubmed-meshheading:16636336-Diarrhea,
pubmed-meshheading:16636336-Drug Administration Schedule,
pubmed-meshheading:16636336-Female,
pubmed-meshheading:16636336-Fluorouracil,
pubmed-meshheading:16636336-Humans,
pubmed-meshheading:16636336-Infusions, Intravenous,
pubmed-meshheading:16636336-Male,
pubmed-meshheading:16636336-Middle Aged,
pubmed-meshheading:16636336-Neoadjuvant Therapy,
pubmed-meshheading:16636336-Neutropenia,
pubmed-meshheading:16636336-Organoplatinum Compounds,
pubmed-meshheading:16636336-Radiotherapy, Adjuvant,
pubmed-meshheading:16636336-Rectal Neoplasms,
pubmed-meshheading:16636336-Thrombocytopenia,
pubmed-meshheading:16636336-Treatment Outcome
|
pubmed:year |
2006
|
pubmed:articleTitle |
Phase I/II study of preoperative oxaliplatin, fluorouracil, and external-beam radiation therapy in patients with locally advanced rectal cancer: Cancer and Leukemia Group B 89901.
|
pubmed:affiliation |
Massachusetts General Hospital Cancer Center, Boston MA 02114, USA. dpryan@partners.org
|
pubmed:publicationType |
Journal Article,
Multicenter Study,
Clinical Trial, Phase II,
Clinical Trial, Phase I,
Research Support, N.I.H., Extramural
|