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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-2-28
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pubmed:abstractText |
It is proposed that the energy-transducing system of the first cellular organism and its precursor was fueled by the oxidation of hydrogen sulfide and ferric sulfide to iron pyrites and two [H+] on the outside surface of a vesicle (the cell membrane), with the concomitant reduction of CO or CO2 on the interior. The resulting proton gradient across the cell membrane provides a proton-motive force, so that a variety of kinds of work can be done. It is envisioned as providing a selective advantage for cells capable of harvesting this potential. The proposed reactants for these reactions are consistent with the predicted composition of the Earth's early environment. Modern-day homologs of the ancestral components of the energy-transducing system are thought to be membrane-associated ferredoxins for the extracellular redox reaction, carbon monoxide dehydrogenase for the carbon fixation reaction, and ATPase for the harvesting of the proton gradient. With a source of consumable energy, the cell could drive chemical reactions and transport events in such a way as to be exploited by Darwinian evolution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphatases,
http://linkedlifedata.com/resource/pubmed/chemical/Aldehyde Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/Iron-Sulfur Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Multienzyme Complexes,
http://linkedlifedata.com/resource/pubmed/chemical/Protons,
http://linkedlifedata.com/resource/pubmed/chemical/carbon monoxide dehydrogenase
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-2844
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-304
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1663558-Adenosine Triphosphatases,
pubmed-meshheading:1663558-Aldehyde Oxidoreductases,
pubmed-meshheading:1663558-Biogenesis,
pubmed-meshheading:1663558-Electrons,
pubmed-meshheading:1663558-Energy Metabolism,
pubmed-meshheading:1663558-Iron-Sulfur Proteins,
pubmed-meshheading:1663558-Multienzyme Complexes,
pubmed-meshheading:1663558-Oxidation-Reduction,
pubmed-meshheading:1663558-Protons,
pubmed-meshheading:1663558-Temperature,
pubmed-meshheading:1663558-Thermodynamics
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pubmed:year |
1991
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pubmed:articleTitle |
The first cellular bioenergetic process: primitive generation of a proton-motive force.
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pubmed:affiliation |
Department of Biology, Indiana University, Bloomington, IN 47405, USA.
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pubmed:publicationType |
Journal Article
|